In short. The CO2 resurfacing complications that should change your decision: infection, delayed healing, scarring and permanent colour change, and how each is managed.

Key points

  • A written plan that says what will be treated, how deep, what the healing week involves, what to do if something goes wrong, and who to contact out of hours.
  • Inside a hospital, that contact is backed by dermatology and surgical cover rather than a mobile number.
  • Ask what happens if you develop a problem on a Sunday night.

Every treatment has a consent list. The useful question is which risks are common enough to plan around, which are rare but serious, and which should change your mind about having the treatment at all.

The expected, which is not the same as a complication

Redness, swelling, oozing, crusting and itching are part of the treatment rather than complications of it. So is a period of increased sensitivity, and so is the pinkness that persists for weeks after the surface closes. Patients who were warned about these cope with them; patients who were not often think something has gone wrong when nothing has.

Infection

Open skin can become infected, and the risk is highest in the first week. Antiviral cover is ordinarily prescribed, because a cold sore erupting across healing skin can leave scarring, and bacterial infection is treated promptly with antibiotics. The signs to act on are increasing pain after the third day, spreading redness, heat, discharge, or a fever. Treated early, infection usually settles without lasting harm. Ignored, it can scar.

Delayed healing and scarring

Some areas heal more slowly than others, and healing that lags raises the risk of a scar. Scarring after resurfacing is uncommon but real, and it is more likely after infection, after treatment that was too deep for the skin, and in people with a keloid tendency. It is also more likely on the neck and on thin skin. A scar that forms is treatable, but it is easier to avoid than to correct.

What the clinic owes you before treatment

A written plan that says what will be treated, how deep, what the healing week involves, what to do if something goes wrong, and who to contact out of hours. Inside a hospital, that contact is backed by dermatology and surgical cover rather than a mobile number. Ask what happens if you develop a problem on a Sunday night.

Permanent colour change

Darkening after treatment is common and usually temporary. Lightening is uncommon and can be permanent, because pigment cells that are lost do not reliably return. It is the complication with no good correction, and the reason resurfacing depth is chosen conservatively in darker skin and on thin areas. It is also the reason an aggressive plan deserves to be questioned rather than admired.

Seek review the same day if

  • Pain is worsening after the third day, or one area is hotter and more swollen than the rest.
  • You have a fever, spreading redness, or discharge from the treated skin.
  • You notice blistering, dusky or grey patches, or a sore that is not crusting like the rest.

None of this makes resurfacing a bad treatment. It makes it a treatment with a real consent conversation attached, and that conversation is worth more than the form you sign at the end of it.

Related reading

Frequently asked questions

How likely is scarring after CO2 resurfacing?

Uncommon, but real, and the risk is not spread evenly. It rises after infection, after treatment that was too deep for the skin being treated, in people with a keloid tendency, and on the neck and other thin-skinned areas. A scar that does form can be treated, but avoiding one is far easier than correcting one afterwards.

What are the signs of infection after resurfacing?

Pain that increases after the third day instead of easing, redness or heat spreading beyond where it was, discharge that smells, and fever. Cold sores erupting across healing skin are a particular concern, which is why antiviral cover is ordinarily prescribed. Infection treated early usually settles without lasting harm; ignored, it can scar.

Can a complication be corrected afterwards?

Some can and some cannot. Infection caught early usually resolves. A scar can be treated but not erased. Pigment that has darkened usually settles with time, protection and prescribed creams. Pigment that has been lost is the one with no good correction, which is why depth is chosen conservatively in the first place.

Risks & Limitations

  • The treated surface is usually open for five to seven days, weeping and crusting, with redness that persists for weeks afterwards.
  • Post-inflammatory hyperpigmentation is the commonest unwanted effect; it is more frequent and more stubborn in darker skin and can take months to settle.
  • Pigment loss (hypopigmentation) is uncommon but can be permanent, and there is no reliable way to restore pigment that has been lost.
  • Infection of open skin, which is why antiviral cover is ordinarily prescribed; increasing pain after the third day, spreading redness or fever needs same-day review.
  • Scarring, uncommon but real, and more likely after infection, after treatment that was too deep for the skin, on the neck, and in people with a keloid tendency.
  • The improvement is long-lasting but not permanent, and sun exposure after treatment fades it faster than anything else.

When to Seek Care

  • Increasing pain after the third day, or one area much hotter and more swollen than the rest of the treated skin.
  • Fever, spreading redness, or discharge from the treated area.
  • Blistering, dusky or grey patches, or a sore that is not crusting like the rest of the face.
  • A cold sore erupting across healing skin, which should be reported the same day.
  • Swelling that makes it difficult to see, or any new change in vision, which needs urgent review.

References & Further Reading

  • American Society for Laser Medicine and Surgery (ASLMS) — patient information on laser and energy-based treatment
  • American Academy of Dermatology (AAD) — guidance on laser resurfacing and post-inflammatory hyperpigmentation
  • National Institute for Health and Care Excellence (NICE, UK) — relevant guidance on skin treatments
  • Cochrane Library — systematic reviews in skin resurfacing and scar management

Medically reviewed by Ke He, MD (何锞), Deputy Director & Head of Skin & Laser Aesthetics. Last reviewed: 19 September 2026.

This page is patient education, not medical advice, and it does not cite individual studies. Discuss your own case with a qualified clinician. To arrange an assessment at Chongqing West District Hospital, see Contact & Consultation.